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How Lyme Disease Affects the Nervous System?


Lyme disease becomes a serious illness if not diagnosed at the early stage and is caused by tick bites. If it’s not treated in time, it can affect the nervous system, leading to what’s called neurological Lyme disease.
The neurological lyme disease symptoms may cause memory issues, and even paralysis.
In this article, let’s learn and understand how Nervous system and Lyme disease are related. Understand its symptoms and appropriate treatments that are available.
What Are the Neurological Lyme Disease Symptoms?
- Neurological Lyme disease symptoms include headaches, memory problems, trouble concentrating, facial paralysis, and tingling or numbness in the arms and legs. These symptoms can occur if the bacteria reaches the brain, spinal cord or nerves.
- When Lyme spreads to the nervous system, it can cause inflammation in vital areas like the brain and spinal cord.
- This can result in cognitive impairments, coordination, and memory issues. Because of this it is recommended to get diagnosed early and get proper treatment. If left untreated, these symptoms can prolong and worsen results in long-term lyme disease nerve damage that can be hard to reverse.

What Is Neuroborreliosis, and How Is It Linked to Lyme Disease?
- Neuroborreliosis is a serious form of neurological Lyme where the infection spreads to the central nervous system. Neuroborreliosis is a severe issue that results in meningitis, facial paralysis, and memory problems.
- Neuroborreliosis can be caused to a person when the bacteria enters into the brain and spinal cord. This severity of the disease is because of intense inflammation in the specific region, resulting in severe headaches, confusion, and even issues with motor skills. It results in permanent damage to your body that affects the ability to think, memory, or motor skills, if left unnoticed.
- Thankfully, with the right antibiotics, many people recover fully, but early treatment is critical.

How Is Nervous System Lyme Disease Diagnosed?
- Nervous system lyme disease is diagnosed through blood tests, and sometimes spinal fluid tests are required. These tests help you confirm whether it has affected your brain or nerves.
- Initially, the doctor notices your symptoms and checks whether you have memory issues, numbness or pain. Blood tests show the ability of your to fight against lyme bacteria. In some cases, doctors may ask you to check for spinal fluid tests to confirm inflammation or infection in the central nervous system.
- Early and accurate diagnosis is crucial for the right treatment and avoids long-term health issues.

What Treatments Are Available for Neurological Lyme?
- Treatment for neurological Lyme often involves antibiotics, either pills or through an IV for more severe cases. Medications combined with physical therapy can also help manage symptoms.
- For mild cases, oral antibiotics can usually clear up the infection. More serious cases involving the brain or nerves might require intravenous (IV) antibiotics to ensure the medicine reaches the infected areas.
- Along with antibiotics, physical therapy can help if you have difficulties with movement, while pain medications can ease nerve discomfort. Acting quickly to treat the infection gives you the best chance of full recovery.
Can Lyme Cause Cognitive Problems?
- Yes, Lyme can cause cognitive problems like memory loss, difficulty concentrating, and brain fog. These cognitive issues are the effects when the bacteria infect the brain, causing inflammation.
- People with neurological Lyme often report feeling “foggy” or struggling to remember things. This infection results in improper functioning of the brain.
- The infected person may experience mild forgetfulness to severe health issues that affect their daily activities. With early treatment, many people see improvements, but long-term cases may need additional therapies like cognitive training to help regain mental sharpness.

Conclusion
- Living with neurological Lyme disease can be tough, but understanding it is the first step toward recovery. Early diagnosis and treatment are crucial for avoiding serious complications like nerve damage or cognitive issues.
- If you think Lyme might be affecting your nervous system, don’t wait to seek help. Talk to a doctor, get the right tests, and start treatment as soon as possible.
- The sooner you take action, the better your chances of getting back to a healthy, normal life. Remember, with the right care and support, recovery is possible.
References
- Fallon BA, Madsen T, Erlangsen A, Benros ME. Lyme Borreliosis and Associations With Mental Disorders and Suicidal Behavior: A Nationwide Danish Cohort Study. Am J Psychiatry. 2021 Oct 1; 178(10):921-931. doi: 10.1176/ appi.ajp.2021.20091347
- Ganesh Bushi, Ashok Kumar Balaraman, Shilpa Gaidhane, Suhas Ballal, Sanjay Kumar, Mahakshit Bhat, Shilpa Sharma, M Ravi Kumar, Aashna Sinha, Mahalaqua Nazli Khatib, Nishant Rai, Sanjit Sah, Ambanna Yappalparvi, Shailesh Kumar Samal, Doddolla Lingamaiah, Muhammed Shabil,
- Lyme disease associated neurological and musculoskeletal symptoms: A systematic review and meta-analysis, Brain, Behavior, & Immunity – Health, https://doi.org/10.1016/j.bbih.2024.100931.
- Clinical and epidemiological features of Lyme borreliosis in Bulgaria. Wien Klin. Wochenschr., 116 (1–2) (2004), pp. 42-46. Scopus | Google Scholar.
- Garcia-Monco JC, Benach JL. Lyme Neuroborreliosis: Clinical Outcomes, Controversy, Pathogenesis, and Polymicrobial Infections. Ann Neurol. 2019 Jan;85(1):21-31. doi: 10.1002/ana.25389. PMID: 30536421; PMCID: PMC7025284.