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Lyme Disease: Symptoms, Diagnosis, and Treatment Options

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The bite of an infected black-legged tick causes lyme disease. It is a tick-borne illness that is mainly induced by the presence of the bacteria Borrelia burgdorferi

When people are engaged in outdoor activities, the chances are more to get exposed. Learning about the lyme condition and the areas where people get more exposed to such diseases can help to prevent it. 

In case of lyme disease early detection is more crucial to avoid long-term health problems. Fever, exhaustion, and bull’s eye rash are the common indicators of this symptom. Getting informed and taking proactive steps is crucial to improve their health. Let’s deep dive into this blog and understand more on the symptoms, diagnosis, and treatment options of lyme illness.

How Does Lyme Disease Transmission Occur?

Lyme disease occurs when an infected tick bites a human, it transmits the bacteria into the blood through its saliva. Here is how it happens.

Tick attachment to the human body:

The tick has to remain attached to the skin for a period of 36-48 hours to be able to transfer the bacteria.

Environmental Risks:

Spending long hours in a woody and grassy area, bushy lands, or forests expands the risk of tick infestation.

Transmission:

When the tick bites the bacteria known as Borrelia burgdorferi transmitted  into the blood through the saliva while the tick is feeding.

After engaging in outdoor activities, make sure to check for ticks. If you find the tick and removing it immediately can eliminate the risk of infection.

Signs and Symptoms of Lyme Disease

It is common for people to confuse symptoms of Lyme disease with other illnesses. So, it is significant to notice the early signs of Lyme disease and confirm it. The signs include:

1. Early Symptoms (3-30 Days After Tick Bite)

Erythema Migrans (EM)

Nearly 70% – 80% of cases, bull’s eye rash (a ring-like red rash) is found at the area of tick bite and it expands over the days.

Flu-like Symptoms

Lyme illness resembles flu-like symptoms that includes fever, headaches, chills, fatigue, enlarged lymph nodes, and muscle soreness or joint pain

2. Later Symptoms (Weeks to Months After Tick Bite)

It is highly advised that they contact a healthcare professional and know the signs of Lyme conditions.

What Causes Lyme Disease?

The bacterium Borrelia burgdorferi is the primary cause of Lyme conditions. Some of the factors contribute to the risk of infection are as follows:

Geographical Location:

States such as the northeastern region and the upper midwestern region in the United States have a high degree of tick density. These areas where people will have a higher chance of getting infected.

Outdoor Activities:

Increasing chances of being exposed by hiking, camping, and gardening.

Tick Behavior

The nymphal stage or larval stages of a tick are the worst in transmitting the disease as they are so tiny that they are hard to notice.

Lack of Prevention

Since there are no specific clothes that protect or tick sprays to prevent lyme, they are more likely to get bitten.

Getting informed on these causes can help you to take preventative measures that reduce the risk of getting affected by lyme.

How is Lyme Disease Diagnosed?

Lyme disease diagnosis involves clinical assessment and laboratory tests. Let’s look into how practitioners diagnose Lyme illness.

Medical History

The physician inquires about the health history and the developed symptoms.

Physical Exam

Examine physically for the bull’s-eye rash or any other signs of Lyme condition.

Laboratory Tests

Some of the laboratory tests are advised like

ELISA Test

Assesses the presence of antibodies to Borrelia burgdorferi.

Western Blot

The confirmatory test for a positive ELISA test.

In its early stages, blood tests may not detect the disease. So diagnosis often depends on symptom patterns and exposure history.

Treatment Options and Prevention

Pharmacological Treatment

Antibiotics

At an early stage of disease physicians give antibiotics. A regular 10-21 day course is advised.

Pain Management

Over-the-counter medications and anti-inflammatories can treat joint pain and swelling.

Non- Pharmacological Treatment

Avoid Tick Habitats

Avoid going to wooded or grassy areas where ticks are highly populated and especially during the seasonal months.

Wear Protective Clothing

Wear fully covered clothes like pants, long sleeves, and closed shoes.

Use Tick Repellents

Use EPA-approved tick repellents. It must be applied on clothes and any exposed skin if going into areas where ticks are highly populated.

Conduct Tick Checks

If you are in a tick populated area ensure that you check yourself and your clothes completely once you are from outdoors. If you have pets that have ‘played’ in the outdoors make sure it has not been affected by the tick bite.

Maintain Your Yard

Keep your yard clean, remove the leaf debris and trimmings, and set aside areas free of ticks in your yard.

The Key Takeaway

Lyme disease is the tick-borne illness, it affects the individual seriously if left untreated or unnoticed. But  it can be prevented and early detection can help to treat it effectively. Consider proactive measures such as using tick repellents, wearing protective clothing, and conducting regular tick checks after spending time outdoors to reduce your risk. Knowing the symptoms, diagnosis and treatment options helps with timely intervention and proper care which can help you effectively manage and recover from Lyme conditions.

References

  1. Alliance GL. About Lyme – Global Lyme Alliance. www.global lyme alliance.org. 2023. [GLA]
  2. ‌CDC. Signs and Symptoms of Untreated Lyme Disease [Internet]. Lyme Disease. 2024. Available from: https://www.cdc.gov/lyme/signs-symptoms/index.html 
  3. Bahadori A, Ritz N, Zimmermann P. Diagnosis and treatment of Lyme disease in children. Archives of Disease in Childhood Education and Practice Edition. 2023 Dec 1;108(6):422–8. [PubMed] 
  4. How to Treat Lyme Disease: A Patient Reflects. Globallymealliance.org. 2024 [cited 2025 May 12]. Available from: https://www.globallymealliance.org/blog/reflections-on-how-to-treat-lyme-disease

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