
Could increasing your body temperature actually help with fighting Lyme? This question is being raised more and more as several people are becoming interested in hyperthermia—a therapy involving the use of controlled heat to kill infections in the body and boost the immune response.
Once chronic Lyme symptoms remain long after traditional antibiotic treatment, it stands to reason that patients will look to find alternative approaches for relief. Hyperthermia may offer a new source of relief by weakening the bacteria that cause Lyme disease and by supporting the body's natural healing.
But how effective is hyperthermia really? Let’s see if heat therapy is the piece of the puzzle that is necessary for your recovery"
What Is Hyperthermia Therapy and How Does It Work?
Hyperthermia therapy is a treatment where the body's core temperature is intentionally increased, with the goal of launching immune activity and fighting infection.
Unlike its natural fever counterpart, it provides artificial fever responses as it will use devices such as thermal chambers or medically induced fever to elevate the body's temperature from 38.5°C (101.3°F) to 41.6°C (106.9°F).
- Most sessions will last from 30 minutes to several hours and may be repeated over multi-day or multi-week installments.
- The goal is to artificially mimic what the body does in fever response, so that it can boost immune function, open up blood flow in the body, and target heat-sensitive pathogens such as Borrelia burgdorferi, the bacteria related to Lyme disease.
- Hyperthermia therapy can help in situations that don't respond to conventional treatment, especially chronic or persistent infections.
How Does Hyperthermia Target Lyme Bacteria?
Lyme bacteria, like Borrelia burgdorferi, are skilled at evading treatment from the immune system and medications through hiding in tissues, forming biofilms, and changing into antibiotic-resistant forms.
- Research shows Borrelia are sensitive to heat. When the body is heated, especially over 106°F (41°C), the bacteria may weaken, or they may “come out of hiding,” making it possible for antibiotics to work better.
- Hyperthermia may disrupt biofilms that protect bacteria and allow the bacteria to hide.
- Hyperthermia also increases blood flow and improves lymphatic drainage—helping flush toxins out of the body and reduces inflammation.
- Hyperthermia also naturally mimics fever and activates the immune system—by creating a strong reaction, increasing the amount of white blood cells and natural killer cells to attach to residual infections.
- All and all, hyperthermia is a multi-faceted treatment that works with the immune system while disrupting the stealth tactics of Lyme pathogens.
Is There Scientific Evidence That Hyperthermia Helps Lyme Patients?
There are well-documented biological principles to support heat use and killing Borrelia bacteria, and a known thermal sensitivity. Laboratory studies document that Borrelia strains begin to die at temperatures above 106°F (41.1°C).
Of course, it wouldn't be safe to maintain high body temperatures for long periods of time, but short, administered periods of elevated core temperature may reduce the bacterial load over an extended time period.
Heat therapy also stimulates the immune system through immune cells such as macrophages and natural killer cells, enhances blood flow and oxygenation, defeats protective biofilms that contain persistent bacteria, starts induced sweating for detoxification, and warmth alleviates some of the inflammation and stiffness in muscles that accompany chronic Lyme disease.
Because of those effects, hyperthermia for Lyme disease appears to be a viable method to organize a complementary approach to bacteria, including the residual symptoms of Lyme disease.
Real life Stories of Lyme Recovery with Hyperthermia
Many Lyme patients share stories of hyperthermia therapy with positive reports.
- Some have recovered to a point of symptom reduction such as brain fog, joint pain, and fatigue—especially after experiencing weekly heat treatments or whole-body hyperthermia treatments from specialty clinics.
- Patients often experience similar trends, including temporary detox symptoms (feeling flu-like), and then report increased energy, sleep, and mental focus.
- Patients will often report that elevated symptoms after treatments are due to bacterial die off. Although there is no regulation of treatment availability, consistent treatments appear to yield greater results.
- Although patients can provide experiences as they are the outcome of their results, it is not clinical evidence.
Hyperthermia is best utilized as part of a supportive protocol that includes: adequate hydration, a healthy diet, antimicrobials, and detox support.
Side Effects of Hyperthermia for Lyme Disease?
While hyperthermia therapy offers exciting treatment options, people with other health issues could experience unwanted side efffects related to the therapy.
- The most common side effects that may arise from hyperthermia include dehydration, from sweating heavily, and electrolyte imbalance, which affects muscles and heart function.
- Some individuals may also experience Herxheimer reactions by experiencing an acute exacerbation of symptoms, due to toxins released from dying bacteria.
- Additionally, in rare cases, you may see overheating and heat stroke, if hyperthermia is not properly administered.
- Individuals with cardiovascular conditions might have even greater risk, due to stress on the heart.
- For these reasons, hyperthermia should always be administered in consultation with a Lyme-experienced practitioner whose job it is to be aware of your vitals (i.e., blood pressure, heart rate, etc.) and hydration status, while observing response to the therapy.
Can Hyperthermia Replace Antibiotic Treatment for Lyme Disease?
While hyperthermia is certainly not a replacement for antibiotic treatment for Lyme disease, particularly in its early or acute stages, antibiotics remain the primary treatment and usually eliminate Borrelia bacteria as the best-established convention.
- For symptomatic patients who continue to have symptoms after completing their antibiotic round, often labelled as chronic or persistent Lyme, hyperthermia may play a role as a supportive or adjunctive modality.
- In conjunction with antimicrobial herbs, detox protocols, immune-supporting therapies, and customized lifestyle changes - hyperthermia may enhance the body's innate healing mechanisms.
- The goal of this integrative approach is not to replace conventional treatment, but to enhance the recovery response in more complex or treatment-resistant cases.
Final Thought
Hyperthermia therapy is a potential option that can act as an adjunctive therapy in Lyme disease, especially for patients who have chronic presentations after standard antibiotic treatment.
- Hyperthermia therapy harnesses controlled heat to help weaken, kill or alter the bacteria, while also promoting your immune response and the detoxification process.
- This therapy does not replace antibiotics, rather it is an adjunct treatment modality that can help address recovery in chronic Lyme disease patients.
- Patients are encouraged to work with a Lyme literate healthcare provider to ensure the safety and efficacy of hyperthermia therapy in the context of an overall comprehensive and tailored program, with physician oversight.
Reference
- Heckel-Reusser S. Whole-Body Hyperthermia (WBH): historical aspects, current use, and future perspectives. In: Springer eBooks [Internet]. 2022. p. 143–54. Available from: https://www.ncbi.nlm.nih.gov/books/NBK593451/
- Gazel, D., Akdoğan, H., BüyüktaşManay, A., Erinmez, M., & Zer, Y. (2024). The potential of therapeutic hyperthermia to eradicate Staphylococcus aureus bacteria; an in vitro study. Journal of Thermal Biology, 120, 103812. https://doi.org/10.1016/j.jtherbio.2024.103812
- Lopez, J., Hovius, J. W., & Bergström, S. (2020). Pathogenesis of Relapsing Fever. Current Issues in Molecular Biology, 42, 519. https://doi.org/10.21775/cimb.042.519
- Medizin E. The extracorporeal hyperthermia perfusion for the treatment of Lyme disease - Zentrum der ErweitertenMedizin [Internet]. Zentrum Der ErweitertenMedizin. 2021. Available from: https://www.erweiterte-medizin.de/en/news/ehp-hyperthermia-treatment-lyme-disease/
- Skar GL, Blum MA, Simonsen KA. Lyme Disease [Internet]. StatPearls - NCBI Bookshelf. 2024b. Available from: https://www.ncbi.nlm.nih.gov/books/NBK431066/